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Paradigm Biopharmaceuticals Ltd
Level 15, 500 Collins St
Phone: +61 396295566p:+61 396295566 MELBOURNE, VIC  3000  Australia Ticker: PARPAR
Business Summary
Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company is engaged in discovering, developing, and delivering pharmaceutical therapies. It is focused on the development of injectable pentosan polysulfate sodium (iPPS/PPS) for the treatment of osteoarthritis (OA) and mucopolysaccharidosis (MPS). Pentosan polysulfate sodium is a semi-synthetic drug manufactured from the wood chips of European beech trees. Extracted glucurono-xylans are sulfated to produce a negatively charged product that mimics glycosaminoglycans (GAGs). It develops PPS under the brand name Zilosul. PPS also inhibits the synthesis of the metalloproteinase, MMP-3 (Troeberg) involved in degrading cartilage. PPS also include treatment of joint function, mobility, and pain in patients with MPS; treating alphavirus-induced arthralgia (such as Ross River virus and Chikungunya); chronic heart failure (HF) and acute respiratory distress syndrome (ARDS).

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
6/30/20246/30/2024Yes----

Industries
SIC Code Description
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Executive Chairman of the Board, Managing Director PaulRennie 11/22/2022 5/2/2014
Chief Financial Officer, Company Secretary Abby M.Niven 3/3/2023 3/3/2023
Executive Director, Chief Medical Officer DonnaSkerrett 7/1/2022 7/3/2020
Non-Executive Director Matthew J.Fry 3/4/2024 3/4/2024
Non-Executive Independent Director AmosMeltzer 12/9/2020 12/9/2020

General Information
Outstanding Shares: 350,364,346 (As of 6/30/2024)
Shareholders: 13,758
Stock Exchange: ASX
Fax Number: +61 396295466


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Wednesday, November 20, 2024