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Applied Therapeutics Inc
545 5TH AVENUE, SUITE 1400
Phone: (212) 220-9226p:212 220-9226 NEW YORK, NY  10017  United States Ticker: APLTAPLT
Business Summary
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
9/30/202412/31/2023YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research
2834 Pharmaceutical preparations

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Chairman of the Board, President, Chief Executive Officer, Founder ShoshanaShendelman 45 1/1/2016
Chief Financial Officer and Principal Financial Officer, Director Leslie D.Funtleyder 54 11/20/2023 6/1/2016
Chief Operating Officer and Chief Business Officer ConstantineChinoporos 58 12/28/2023 12/28/2023
7 additional Officers and Directors records available in full report.

General Information
Number of Employees: 37 (As of 9/30/2024)
Outstanding Shares: 116,356,474 (As of 11/6/2024)
Shareholders: 26
Stock Exchange: NASD
Fax Number: (302) 636-5454


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Wednesday, November 20, 2024